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Studies have shown that morusine can kill liver cancer cells, in particular hepatocellular carcinoma, and reduce their growth.
The morusine blocks certain pathways that cancer cells use to grow and spread. This natural compound also prevents the formation of new blood vessels, which tumours need to grow, making the morusine a promising candidate for the treatment of liver cancer.
Nasopharyngeal carcinoma
The morusine has shown potential in the treatment of nasopharyngeal carcinoma (a type of cancer that affects the nasopharynx, an area behind the nose and above the throat) by inhibiting the movement and invasion of cancer cells. Research indicates that morusine may block the expression of MMP-2, a protein linked to the spread of cancer and poor results in nasopharyngeal carcinoma (NSC). Resembling the activity of this protein, the morusine could help reduce the risk of NPC metastasis.
Prostate cancer
In experiments on prostate cancer cell lines, moroby has been shown to reduce the survival of cancer cells while sparing healthy prostate cells. The compound blocks a key signalling pathway (SRC/JAK2/STAT3), which is essential for the survival of cancer cells. By removing this pathway, the morusine has triggered the death of cancer cells, especially the proteins that present them to prevent apoptosis.
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