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This may be the first sign of Alzheimer’s: In 80% of cases, people will develop the disease

Alzheimer’s, a neurodegenerative disease that affects millions of people worldwide, is known for its devastating impact on memory and cognitive function. However, identifying its early signs can be key to early diagnosis and better management. Recent research has highlighted that an early symptom, mild memory loss associated with difficulty recalling recent events, can be a critical indicator.

According to studies, up to 80% of people who experience this symptom, known as mild cognitive impairment (MCI), will develop Alzheimer’s in the following years. This article explores this early sign, its meaning, and how to take action to protect brain health, with a clear, professional, and accessible approach.

What is Alzheimer’s and why is it important to detect it early?

Alzheimer’s is a progressive disease that affects brain cells, causing memory loss, thinking difficulties, and behavioral changes. According to the Alzheimer’s Association (2025), more than 55 million people are living with dementia worldwide, with Alzheimer’s accounting for up to 70% of cases. Although there is no cure, early detection allows access to treatments that slow its progression, improve quality of life, and plan for the future.

Dr. Maria Carrillo, scientific director of the Alzheimer’s Association, explains: “Identifying early signs, such as mild cognitive impairment, is crucial because it gives us a window to intervene before brain damage becomes extensive.” The transition from mild symptoms to Alzheimer’s can take years, underscoring the importance of acting at the first signs.

The First Sign: Mild Cognitive Impairment (MCI)

Mild cognitive impairment is an intermediate state between normal aging and dementia. It is characterized by memory or thinking problems that are more noticeable than typical age-related changes, but not severe enough to significantly interfere with daily life.

According to a study published in Neurology (2024), 80% of people with amnestic MCI (which primarily affects memory) will develop Alzheimer’s within 5 to 10 years.

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